This story originally aired in the April 27, 2025 episode of Inside Appalachia.
There’s a new breed of herbalist and forager emerging in Appalachia. Health professionals are increasingly incorporating folk cures into medical treatments. Nowhere is that more evident than in dealing with poison ivy.
MaryBeth Babos and Marybeth Mitcham are both scientists who practice folk cures. Babos, a pharmacist, describes herself as a wannabe ethnobotanist. “I started learning about plants when I was in third grade from a library book, and I’ve been loving it ever since.”
Photo Credit: Wendy Welch/West Virginia Public Broadcasting
Mitcham is also an herbal enthusiast and forager. “I work for George Mason University as an assistant professor at George Mason University and the director of the Master of Public Health Program. I’m an herbal enthusiast and I like to eat plants.”
While traveling together in the same public health circles, they discovered a mutual enthusiasm for making medicines at home. And they have a lot to say about home remedies for one of nature’s scourges: poison ivy.
Babos says when it comes to poison ivy, different people will have different experiences. “I’m blessed that I only get a mild itchy rash. I’ve had poison ivy more times than I could count, but for me, it’s just no worse than a mosquito bite.”
About 80% of people will develop an itchy series of blisters, but about 15% will have a reaction so severe, it resembles chemical burns. Babos says it’s all because of an oil in the plant that contains a chemical called urushiol.
“Urushiol contains free sulfhydryl groups that form covalent bonds with constituents of our skin, and it’s the urushiol bound to our skin that causes our CD 8T cells to react, causing what’s known as a delayed type hypersensitivity.”
In other words, urushiol on your skin will make you itch, so you need to get it off quickly. The fastest way is to wash with soap and water.
But if you’re in the woods, nowhere near soap and water, you can try a few local plants to counteract the urushiol: for instance, jewelweed. It often grows near poison ivy, and is easy to spot.
“Jewelweed is noticeable because it has bright green leaves and it has flowers that are bright orangey yellow,” says Mitcham.
And it is easy to use immediately, adds Babos. “You can squish up the plant – it has kind of a really juicy stalk – and put that juice on the spot that touched the poison ivy, and it may neutralize the urushiol so that you don’t get the rash.”
Another plant that’s been used for centuries is broadleaf plantain. It grows all over Appalachia and many gardeners think of it as a weed. Pluck a leaf, smash it up and rub it on.
Photo Credit: Wendy Welch/West Virginia Public Broadcasting
Plantain doesn’t die back in winter, which is good, because neither does poison ivy, says Babos. “You can get poison ivy rash in the winter, even in the dead of winter, from contacting the plant.”
Photo Credit: Wendy Welch/West Virginia Public Broadcasting
There is another plant-based option that works in cold weather. Truly desperate hikers can scrub the affected area with oak leaves or the inside of peeled oak bark or witch hazel bark – although it works better to make a potion from these ahead of time and carry it with you, Babos says. “You would boil, soak the acorns and water and get the liquid off. It’ll turn kind of brownish and it’s that liquid that contains the tannins.”
She recommends applying this as soon as you know you’ve touched poison ivy or using it as treatment after the rash appears. The liquid can be preventive or curative.
“If you already have the rash, the sap from the plant will help with the itch, because it’s mildly antihistaminic. It works like an antihistamine,” Babos says.
Don’t worry about breaking the blisters, she adds. “The blisters, if you blister from poison ivy, don’t contain urushiol. They will not make the rash spread.”
Unfortunately, if the oil is still on your skin, you could spread it by scratching.
For most people, Mitcham says, a salve will be the best treatment. She makes one with jewelweed.
“I want it to be very green, very vibrant, and I will gather the leaves, the stems and the flowers, so all [the] top parts of the plant. Then I will bring it home, and I will rinse it under cold, clear water to make sure that I get any buggy passengers off.”
She chops up the jewelweed, stuffs it in a pint jar and pours in a carrier oil.
“A carrier oil is something that’s going to extract the oils that you want from the jewelweed without causing it damage,” Mitcham says. She uses olive oil.
Mitcham seals the jar and simmers it for up to 24 hours in a crockpot. Then she strains out the jewelweed and adds beeswax.
“There you have it. Jewelweed salve 101,” MItcham says.
Native Americans used jewelweed to treat poison ivy, and that knowledge was passed on to early settlers. More recently, academic studies have been conducted supporting many plant-based folk cures. But not everything that’s circulated as a potential home remedy is a good idea, according to Mitcham and Babos. Like bleach.
“I would not personally put bleach on my skin. Not only would it burn, it’s very caustic, and it would cause more damage. It’s generally not a good idea to put bleach on your skin anyway,” Mitcham says.
What about another home treatment, rubbing alcohol?
“Rubbing alcohol topically might help to remove some of the oil, but I don’t know how good it would feel,” Mitcham says.
“Especially if you broke those blisters open, it might burn quite a bit,” Babos adds. She also vetoes another home therapy – butter.
“I worry about … anything occlusive on irritated skin, so butter might be an issue. I just can’t imagine that it would feel good,” she says.
“I’ve heard people using tea bags as a topical applicant,“ Mitcham says, “when it’s cool, of course, because hot tea on a blister is not a good idea.”
While Babos doesn’t believe there would be any harm from a tepid tea bag, she says cold can be much better – as in frozen.
“I do like the concept of jewelweed ice cubes,” she says. “That feels so good when you have that itchy rash.”
A jewelweed ice cube is literally fresh jewelweed frozen into ice cubes and applied directly to the skin. Cold can stop the itch temporarily while the rash heals. But some people try to kill the itch with very hot water, and Babos would like them to stop. “Generally not a good idea to put hot water on a blister.”
If you want to avoid getting a poison ivy rash all together, Mitcham has a piece of advice:
“Remember not to burn poison ivy, because the oils can be carried in the smoke and damage your lungs.”
Another word of caution: “You don’t want to pee in poison ivy,” says Babos. “Been there, done that. You get the rash in some awkward places.”
“And that’s when you’ll want steroids, not jewelweed,” Mitcham adds with a laugh.
In fact, Mitcham says her husband is one of the 15%, the severe reactors. He has to take steroids when he gets poison ivy; the gentler cures of the folk world take longer on those chemical burns. Mitcham also says it’s a good idea when it comes to taking herbal cures to talk to your health care professional, before you do anything, well, rash.
The jewelweed salve recipe Marybeth Mitcham used can be found here.
A song to help identify jewelweed in the wild can be found here.
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This story is part of the Inside Appalachia Folkways Reporting Project, a partnership with West Virginia Public Broadcasting’s Inside Appalachia. Subscribe to the podcast to hear more stories of Appalachian folklife, arts and culture.